Reconciling the mutation-selection balance model with the schizotypy-creativity connection
Identifieur interne : 002218 ( Main/Exploration ); précédent : 002217; suivant : 002219Reconciling the mutation-selection balance model with the schizotypy-creativity connection
Auteurs : Daniel Nettle [Royaume-Uni]Source :
- Behavioral and Brain Sciences [ 0140-525X ] ; 2006-08.
Abstract
Keller & Miller (K&M) make a persuasive case for the role of mutation-selection balance in the persistence of such disorders as schizophrenia. However, there is evidence relating illness liability to creativity, which seems to imply balancing selection. I argue for a hybrid position, where schizotypal personality traits can have fitness advantages or disadvantages, with mutational load and neurodevelopmental conditions determining which outcome is observed.
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DOI: 10.1017/S0140525X06359092
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